Frequently Asked Questions

Anura™ is a general wellness app that uses your mobile phone’s video camera to measure, track and maintain a record of your resting heart rate and stress level based on the blood flow in your face.

It uses Affective Intelligence (developed by Nuralogix) to transform your mobile phone into your personal health AI™.

Anura’s primary goal is to increase people’s awareness of stress and general health.

Anura™ is available for download as both an iOS and an Anroid app.

• Contactless – No sensors to touch. Measurements are taken just like a selfie!

• Quick – A measurement only takes 30 seconds.

• Measure your resting heart rate and stress level. Our Anura Stress Index (ASI) can help you quantify and monitor your stress over time.

• A history of your measurements is saved, and you can share your results (should you choose) with your family, friends or doctor.

• Private – No images or video are saved on your device or transmitted as part of a measurement. Your blood flow information is encrypted when sent to our cloud servers for analysis and your measurement history is stored using the same encryption techniques that are used by banks.

• Use Anura™ often to increase your awareness of stress and general health.

• Completely free!

• Human skin is translucent.

• Light and its respective wavelengths are reflected at different layers below the skin and can be used to reveal blood flow information in the human face.

• This information is contained in conventional videos.

• A technique known as Transdermal Optical Imaging (TOI™) is used to extract blood flow information from the video. This technique was developed by our team of neuroscience, psychology, physiology, signal processing and deep learning experts.

• Anura™ uses your phone’s video camera to extract and send encrypted blood flow information (no video or photo) to the cloud to be processed by our DeepAffex™ Affective Intelligence engine.

• DeepAffex™ applies advanced signal processing and AI models to predict your resting heart rate and stress, then sends these results back to Anura.

Anura is strictly intended for informational and educational purposes and to promote general wellness.

The measurements results provided to you should not be treated as medical advice or to diagnose, treat, cure or prevent and disease, ailment or injury.

Should you have any health-related questions, please call or see your physician or other medical professional.

The +C option refers to Anura™ when operating in the ‘Consumer mode’.

This is the default (non-licensed) operating mode for the Anura™ app whenever it is downloaded/installed from a mass distribution point (e.g. iOS = Apple app store, Android = anywhere).

In this operating mode Anura supports both ‘anonymous’ users (those users who chose NOT to create a DFX login account) as well as ‘registered’ users (those users who DO create DFX login accounts).

Regardless of the user login status all measurements taken by all users are collected/stored/processed under a common global ORGANIZATION label (defaults to NURALOGIX) and with a common global STUDY label (defaults to ANURA).

This is true for both our China DeepAffex™ cloud as well as our International DeepAffex™ cloud engines and services.

Note that this assigns all measurements (data and results) produced by Anura™ users running in +C mode will be directly linked to the ORGANIZATION labelled as ‘NURALOGIX’.

The +E option refers to Anura™ when operating in the ‘Enterprise mode’.

This is a licensed operating mode for Anura™ which provides assignment of both the ORGANIZATION and STUDY configuration to the Enterprise (licensed) values.

This mode allows individually licensed Anura™ apps to produce measurements (data and results) which will be linked on DFX under the (Enterprise) ORGANIZATION and (Enterprise) STUDY configuration.

Note that this operating mode provides any Enterprise (i.e. business) with the means to generate a secure and private collection of measurements (data and results) that may be subdivided into as many STUDIES as required according to its business needs.

The Anura™ for 'Enterprise' STAGE 1 license enables the Enterprise to maintain centralized control over the collection of measurements (data and results) by pre-assigning OPERATORS for measurement collections.

The +E1 option refers to Anura™ ‘Enterprise mode’ using a STAGE 1 license – whereby preassigned DFX OPERATOR users (accounts) are preassigned by the Enterprise to conduct Anura app measurements on behalf of an unlimited number of PARTICIPANTS (subjects).

The STAGE 1 license is distributed as a QR-CODE (matrix barcode) and is used to enable Anura™ ‘Enterprise mode’ when (a) user that has been designated by the Enterprise as an OPERATOR performs a mobile QR-CODE scan of the Enterprise license (key) to activate the Anura app followed by (b) the user then performs a ‘login’ using a preassigned username (account).

Once both steps have been completed the Anura™ app is then enabled for measurements (collection) using the Enterprise assigned ORGANIZATION and STUDY parameters.

Note that STAGE 1 users must have preassigned DFX accounts prior to activating the Anura app on their device (using the QR-CODE license key).

The Anura™ for 'Enterprise' STAGE 2 license enables the Enterprise to conduct fully decentralized collection of measurements (data and results) for an (unlimited) number of individual PARTICIPANTS (subjects).

The +E2 option option refers to Anura™ ‘Enterprise mode’ using a STAGE 2 license – whereby any user that is ‘targeted’ by the Enterprise (i.e. such as a student or an employee) is able to use Anura app to conduct personal measurements but with all results stored under the Enterprise assigned OPERATOR and STUDY values.

The STAGE 2 license is distributed as a QR-CODE (matrix barcode) and is used to enable Anura ‘Enterprise mode’ when (a) user performs a mobile QR-CODE scan of the Enterprise license (key) to activate the Anura app followed by (b) the user then performs an ‘Sign-Up’ or account registration.

Note that STAGE 2 users do not require preassigned DFX accounts prior to activating the Anura™ app on their device (using the QR-CODE license key).

The STAGE 1 (centralized) collection requires pre-assigned Enterprise OPERATOR users to apply their licensed Anura™ (devices) for collecting measurements (data and results) on behalf of subjects according to the prescribed STUDY protocol.

The OPERATOR must enter a unique identifier in Anura™ to track each individual participant/subject/member/student (e.g. a mobile cell #) measurements.

Each OPERATOR may measure an unlimited number of individuals.

There is no limit on the number of measurements collected per individual.

The STAGE 2 (decentralized) collection expands the collection activities to any individuals that are selected to enroll in the STUDY.

Each participant/subject/member/student will use their personally licensed Anura™ (app) to collect measurement(s) on themselves according to the prescribed STUDY protocol.

Every individual must supply unique identification in Anura™ (e.g. their mobile cell #).

There is no limit on the number of measurements any individual may collect.

The Anura app is available for iOS and Android handset/mobile devices.

For iOS based models, Anura works best on iPhone6 handsets and higher.

Anura™ has been validated on the following Android platforms:

• LG model G5 (model RS 988) running Android 7.0, API 24

• LG model V30 (model LG-H933) running Android 8.0.0, API 26

• Google Pixel 2 running Android 9.0.0, API 28

• Huawei Nova2S (HWI-AL00) running Android 8.0.0, API 26

• Huawei P20 Pro running Android 8.1.0

• ViVo X23 (model V1809A) running Android 8.1.0, API 27

• Oppo R17 (model PBEM00) running Android 8.1.0, API 27

The Anura™ heart-rate measurements is accurate to within +/- 1 bpm when compared against electrocardiogram (ECG) measurements.

We began by taking continuous heart rate measurements of a large sample using traditional, contact-based methods (e.g. EKG). We then used this data to generate 3-D models of stress to derive a ground truth measure of stress using three dimensions.

Using TOI™ signals, we obtain heart rate variability (HRV) measures based on time domain, frequency domain, statistical, dynamic systems, and nonlinear methods extracting over 20 features.

By applying advanced machine learning techniques and other statistical methods, we maximized the correspondence between the more than 20 features extracted from the 30 second TOI™ signal and the ground truth.

We then computed the statistical means and standard deviations of the predicted stress values to create a norm based on a Gaussian distribution.

Finally, we converted the predicted stress values into a stress index with 5 levels where 1 is the lowest and 5 is the highest. The difference between each level represents one standard deviation.

The Anura™ heart rate result is calibrated to align with the medically indicated ranges for the human resting heart rate.

The medically indicated range for a "normal" resting heart rate lies between 60 bpm and 100 bpm.

When Anura™ measures a heart rate that falls lower than 60 bpm, the result will be indicated on the "below normal" range (Bradycardia).

When Anura™ measures a heart rate that is above 100 bpm, the result will be indicated on the "above normal" range (Tachycardia).

SNR' is a generalized 3 letter acronym that refers to a "Signal-to-Noise-Ratio" value expressed in logarithmic units of dB (decibels).

Anura™ calculates the SNR by comparing the FBF level (as a separated signal) against the background level (noise floor) and representing the quality as the log-ratio of these two levels.

The Anura™ app indicates the SNR as a "quality metric" that applies to the purity of the extracted Facial Blood-Flow (FBF) data.

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